Homozygous mushroom body neuroblast clones contain fewer cells compared to wild-type clones, and never contain late-born α'/β' or α/β neurons, suggesting a neuroblast-proliferation defect.

Homozygous clones in the γ neurons of the mushroom body extend axons normally during larval development, as seen by their extension into the dorsal and medial lobes at 0 hours after puparium formation (APF). However, at 18 hours APF (a time when most wild-type γ neurons have completely pruned their axons within the dorsal and medial lobes), homozygous γ neurons retain many unpruned axons. Unpruned axons from the homozygous γ neurons persist in adult brains.

Homozygous projection neuron (PN) neuroblast clones have a mild reduction of cell number, and mutant PNs of all three neuroblast lineages show dendrite-targeting defects. Most mutant VA3 adPNs do not innervate the VA3 glomerulus (their normal target). Mutant VA1d PNs do innervate the VA1d glomerulus. Most mutant lPN neuroblast clones do not innervate the DA1 glomerulus. In both adPN and lPN clones, lineage-inappropriate glomeruli are often innervated. Dendrites of mutant vPNs spill outside the antennal lobe with extensive branching into the subesophageal ganglion and the lateral side of the antennal lobe, whereas they occasionally fail to innervate their appropriate target glomeruli (such as DA1 and VA1lm). Dendrites and axons of homozygous single-cell clones target correctly. Most axons of homozygous PNs branch and terminate normally in higher brain centres.

SMC1^LL01162 has abnormal neuroanatomy | somatic clone phenotype, suppressible by Scer\GAL4^Tab2-201Y/EcR^B1.UAS

SMC1^LL01162 has mushroom body | somatic clone phenotype, suppressible by Scer\GAL4^Tab2-201Y/EcR^B1.UAS