FlyBase Allele Report: Dmel\tutl[RNAi.400.UAS]

General Information

Symbol

Dmel\tutl^RNAi.400.UAS

Species

D. melanogaster

Name

FlyBase ID

FBal0243339

Feature type

allele

Associated gene

Dmel\tutl

Associated Insertion(s)

Carried in Construct

P{UAS-tutl.RNAi.400}

Key Links

Transgenic product class

RNAi_reagent

(Ferguson et al., 2009)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ferguson et al., 2009)

Mutagen

in vitro construct

(Ferguson et al., 2009)

Progenitor genotype

Carried in construct

P{UAS-tutl.RNAi.400}

Cytology

Description

UAS regulatory sequences drive expression of a 400bp sequence encoding the N-terminal 123 amino acid sequence of tutl.

(Ferguson et al., 2009)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

tutl

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy, with Scer\GAL4^tutl-GAL4

(Ferguson et al., 2009)

Phenotype Manifest In

photoreceptor cell R7, with Scer\GAL4^tutl-GAL4

(Ferguson et al., 2009)

Detailed Description

Statement

Reference

Expression of tutl^{dsRNA.400.Scer\UAS} under the control of Scer\GAL4^tutl causes R7 terminals to display abnormal lateral extension (tiling).

(Ferguson et al., 2009)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

tutl^RNAi.400.UAS/Scer\GAL4^GMR.long is an enhancer of abnormal neuroanatomy phenotype of Kap-α3^17-76

(Ferguson et al., 2009)

Phenotype Manifest In

Enhancer of

Statement

Reference

tutl^RNAi.400.UAS/Scer\GAL4^GMR.long is an enhancer of photoreceptor cell R7 phenotype of Kap-α3^17-76

(Ferguson et al., 2009)

Additional Comments

Genetic Interactions

Statement

Reference

Reducing the level of tutl through tutl^{dsRNA.400.Scer\UAS} somatic clones in the eye (under the control of flp and Scer\GAL4^GMR.long) enhances the tendency of Kap-α3^17-76 mutant axons to invade neighboring columns.

(Ferguson et al., 2009)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

tutl^RNAi.400.UAS

tutl^{dsRNA.400.Scer\UAS}

tutl^{dsRNA.400.UAS}

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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