FB2026_03 , released September 17, 2026
Allele: Dmel\geko1
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General Information
Symbol
Dmel\geko1
Species
D. melanogaster
Name
FlyBase ID
FBal0243401
Feature type
allele
Associated gene
Dmel\geko
Associated Insertion(s)
P{lacW}geko-1a
P{lacW}geko-1b
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{lacW}geko-1a
    P{lacW}geko-1b
    Cytology
    Description

    Two P{lacW} insertions are present at the same site and in the same orientation in the 5' untranslated region, 37bp downstream from the start of the transcription unit.

    (Shiraiwa et al., 2000)
    Allele components
    Component
    Use(s)
    Inserted element
    P{lacW}
    P{lacW}
    Encoded product / tool
    lacZ
    lacZ
    Tagged with
    Tag:NLS(P)
    Tag:NLS(P)
    Mutations Mapped to the Genome
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Homozygous flies show a reduced attraction to alcohol in an olfactory assay compared to control flies. Mutants also show a reduced olfactory response to 1% acetic acid and 1/32% 3-pentanone compared to controls.

        (Shiraiwa et al., 2000)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Rescued by

        geko1 is rescued by geko+t11

        (Shiraiwa et al., 2000)
        Comments

        gk+t11 rescues the reduced olfactory response of gk1 flies to ethanol.

        (Shiraiwa et al., 2000)
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        Comments
        Comments

        Excision of the insertions reverts the mutant olfactory phenotype.

        (Shiraiwa et al., 2000)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        geko1
        (Shiraiwa et al., 2000)
        gk1
        (Shiraiwa et al., 2000)
        line 1184
        (Shiraiwa et al., 2000)
        Name Synonyms
        Secondary FlyBase IDs
          References (1)