FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ncdTL.ncd.Venus
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General Information
Symbol
Dmel\ncdTL.ncd.Venus
Species
D. melanogaster
Name
FlyBase ID
FBal0243599
Feature type
allele
Associated gene
Dmel\ncd
Associated Insertion(s)
Carried in Construct
P{ncd-ncd.TL.YFP}
Key Links
Transgenic product class
inframe_deletion
(Hallen et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Hallen et al., 2008)
Mutagen
in vitro construct
(Hallen et al., 2008)
Progenitor genotype
Carried in construct
P{ncd-ncd.TL.YFP}
Cytology
Description

Native ncd promoter regulates expression of a fragment encoding the ncd stalk and conserved motor domain (MES-L209-K700) fused at the C terminus to Venus.

(Hallen et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
ncd
Encoded product / tool
ncd
Tagged with
Venus
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Meiosis I spindles are not observed in immature ncdTL.ncd.T:Avic\GFP-YFP.Venus;ncd1 oocytes.

      ncdTL.ncd.T:Avic\GFP-YFP.Venus;ncd1 embryos frequently display abnormally spurred or bridged spindles, nuclei that fail to form spindles, or different-sized spindles or nuclei, all indicative of chromosome loss or mis-segregation. The time required for cycle 10 embryos to progress from nuclear envelope breakdown to midzone formation is significantly longer than in controls.

      (Hallen et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      ncdTL.ncd.Venus fails to rescue ncd1

      (Hallen et al., 2008)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ncdTL.ncd.T:Avic\GFP-YFP.Venus
      ncdTL.ncd.Venus
      Name Synonyms
      Secondary FlyBase IDs
        References (1)