FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\DroncΔD8
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General Information
Symbol
Dmel\DroncΔD8
Species
D. melanogaster
Name
FlyBase ID
FBal0244158
Feature type
allele
Associated gene
Dmel\Dronc
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Kondo et al., 2006)
Progenitor genotype
P{EPgy2}DroncEY08574
(Kondo et al., 2006)
Cytology
Description

Imprecise excision of the progenitor insertion, resulting in a deletion that removes part of the Nc gene.

(Kondo et al., 2006)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Less than 0.1% of homozygotes emerge as adult escapers (most homozygotes die as early pupae). The adult escapers have apparently normal morphology, except that their wings are opaque due to a failure of wing cells to undergo apoptosis.

      Animals that are maternally and zygotically mutant for Nc are embryonic lethal, with almost complete absence of apoptosis.

      (Kondo et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      DroncΔD8
      NcΔD8
      droncΔD8
      (Kondo et al., 2006)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)