FlyBase Allele Report: Dmel\Snoo[2c3]

General Information

Symbol

Dmel\Snoo^2c3

Species

D. melanogaster

Name

FlyBase ID

FBal0244233

Feature type

allele

Associated gene

Dmel\Snoo

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

ethyl nitrosourea

Nature of the Allele

Allele class

Mutagen

ethyl nitrosourea

(Barrio et al., 2007)

Progenitor genotype

P{GSV1}Snoo^M67

(Barrio et al., 2007)

Cytology

Description

Nucleotide substitution: T700A.

(Barrio R. et al., 2007)

Amino acid numbering corresponds to the short Snoo protein.

(Barrio et al., 2007)

Amino acid replacement: F234I.

(Barrio et al., 2007)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

point_mutation

2L:7,975,491..7,975,491 [-]

Nucleotide change:

T7975491A

Reported nucleotide change:

T700A

Amino acid change:

F234I | Snoo-PB; F234I | Snoo-PC; F234I | Snoo-PD; F234I | Snoo-PG

Reported amino acid change:

F234I

(Barrio et al., 2007, Barrio R. et al., 2007)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

fertile | female (with Df(2L)snoN)

(Barrio et al., 2007)

viable (with Df(2L)snoN)

(Barrio et al., 2007)

Phenotype Manifest In

Detailed Description

Statement

Reference

Scer\GAL4^MD-638-mediated expression of the Snoo^2c3 mutant via the P{GSV1} element associated with Snoo^M67 results in wild type wings.

Trans-heterozygotes with Df(2L)snoN are fully viable; females are fertile and complete oogenesis normally.

(Barrio et al., 2007)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressor of

Statement

Reference

Snoo^M67/Snoo^2c3 is a suppressor | partially of wing phenotype of Mad^UAS.cNa, Scer\GAL4^nub-AC-62

(Barrio et al., 2007)

Snoo^M67/Snoo^2c3 is a suppressor | partially of wing vein phenotype of Mad^UAS.cNa, Scer\GAL4^nub-AC-62

(Barrio et al., 2007)

Additional Comments

Genetic Interactions

Statement

Reference

Scer\GAL4^MD-638-mediated expression of the Snoo^2c3 mutant via the P{GSV1} element associated with Snoo^M67 partially suppresses the wing phenotype caused by Scer\GAL4^MD-638-mediated expression of Mad[Scer\UAS.cNa].

(Barrio et al., 2007)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Isolated as a complete revertant of the severe wing phenotype induced by Scer\GAL4^MD-638-mediated expression of Snoo^M67, in which Snoo is expressed from its endogenous locus.

(Barrio et al., 2007)

Separable from: P{GSV1}Snoo^M67.

(Barrio et al., 2007)

Separable from: a lethal second site mutation.

(Barrio et al., 2007)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

GS-M67^2c3

(Barrio et al., 2007, Barrio R. et al., 2007)

M67^2C3

(Barrio et al., 2007)

Snoo^2c3

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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