FlyBase Allele Report: Dmel\Snoo[M67]

General Information

Symbol

Dmel\Snoo^M67

Species

D. melanogaster

Name

FlyBase ID

FBal0244232

Feature type

allele

Associated gene

Dmel\Snoo

Associated Insertion(s)

P{GSV1}Snoo^M67

Carried in Construct

Key Links

Allele class

Mutagen

Delta2-3 transposase

Nature of the Allele

Allele class

Mutagen

Delta2-3 transposase

(Barrio et al., 2007)

Progenitor genotype

Associated Insertion(s)

P{GSV1}Snoo^M67

Cytology

Description

Insertion in 5' UTR of Snoo. In combination with Scer\GAL4 driver lines, causes expression of both Snoo and CG7231 owing to P{GSV1} having Scer\UAS sequences at both ends.

(Barrio et al., 2007)

Allele components

Component

Use(s)

Inserted element

P{GSV1}

misexpression element

Regulatory region(s)

UASt

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die before end of pupal stage | male, with Scer\GAL4^MD-638

(Barrio et al., 2007)

some die during pupal stage | male, with Scer\GAL4^MD-638

(Barrio et al., 2007)

viable

(Barrio et al., 2007)

Phenotype Manifest In

leg, with Scer\GAL4^Dll-md23

(Barrio et al., 2007)

mesonotum, with Scer\GAL4^pnr-MD237

(Barrio et al., 2007)

mesonotum, with Scer\GAL4^ptc-559.1

(Barrio et al., 2007)

wing, with Scer\GAL4^nub-AC-62

(Barrio et al., 2007)

wing, with Scer\GAL4^salm-459.2

(Barrio et al., 2007)

wing | female, with Scer\GAL4^MD-638

(Barrio et al., 2007)

wing vein, with Scer\GAL4^nub-AC-62

(Barrio et al., 2007)

wing vein, with Scer\GAL4^salm-459.2

(Barrio et al., 2007)

wing vein (with Snoo^1D1), with Scer\GAL4^MD-638

(Barrio et al., 2007)

wing vein (with Snoo^F3), with Scer\GAL4^MD-638

(Barrio et al., 2007)

wing vein (with Snoo^K2), with Scer\GAL4^MD-638

(Barrio et al., 2007)

wing vein (with Snoo^R102), with Scer\GAL4^MD-638

(Barrio et al., 2007)

wing vein (with Snoo^S2), with Scer\GAL4^MD-638

(Barrio et al., 2007)

wing vein (with Snoo^V2), with Scer\GAL4^MD-638

(Barrio et al., 2007)

wing vein | female, with Scer\GAL4^MD-638

(Barrio et al., 2007)

Detailed Description

Statement

Reference

Expression of Snoo^M67 using Scer\GAL4^salm-459.2 results in moderate wing size reduction and vein loss.

Expression of Snoo^M67 using Scer\GAL4^nub-AC-62 results in strong wing size decrease accompanied by the absence of all veins.

Expression of Snoo^M67 using Scer\GAL4^MD-638 results in strong wing size decrease accompanied by the absence of all veins in females. Males of this genotype fail to hatch from the pupal case.

Expression of Snoo^M67 using Scer\GAL4^ptc-559.1 or Scer\GAL4^pnr-MD237 results in complete failure to close the heminota.

Expression of Snoo^M67 using Scer\GAL4^Dll-md23 results in failure of anterior-posterior leg patterning and absence of distal segments.

(Barrio et al., 2007)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^salm-459.2, Snoo^M67 has wing phenotype, suppressible by Mad^UAS.cNa, Scer\GAL4^salm-459.2

(Barrio et al., 2007)

Scer\GAL4^salm-459.2, Snoo^M67 has wing vein phenotype, suppressible by Mad^UAS.cNa, Scer\GAL4^salm-459.2

(Barrio et al., 2007)

Scer\GAL4^salm-459.2, Snoo^M67 has wing phenotype, suppressible by Med^UAS.cSa, Scer\GAL4^salm-459.2

(Barrio et al., 2007)

Scer\GAL4^salm-459.2, Snoo^M67 has wing vein phenotype, suppressible by Med^UAS.cSa, Scer\GAL4^salm-459.2

(Barrio et al., 2007)

Scer\GAL4^nub-AC-62, Snoo^M67 has wing phenotype, suppressible by Mad^UAS.cNa, Scer\GAL4^nub-AC-62

(Barrio et al., 2007)

Scer\GAL4^nub-AC-62, Snoo^M67 has wing vein phenotype, suppressible by Mad^UAS.cNa, Scer\GAL4^nub-AC-62

(Barrio et al., 2007)

Scer\GAL4^nub-AC-62, Snoo^M67 has wing vein phenotype, suppressible by Med^UAS.cSa, Scer\GAL4^nub-AC-62

(Barrio et al., 2007)

Suppressor of

Statement

Reference

Snoo^M67/Scer\GAL4^salm-459.2 is a suppressor of wing vein phenotype of Scer\GAL4^salm-459.2, tkv^{Q253D.UAS.cNb}

(Barrio et al., 2007)

Snoo^M67/Scer\GAL4^nub-AC-62 is a suppressor of wing phenotype of Scer\GAL4^nub-AC-62, tkv^{Q253D.UAS.cNb}

(Barrio et al., 2007)

Snoo^M67/Scer\GAL4^nub-AC-62 is a suppressor of wing vein phenotype of Scer\GAL4^nub-AC-62, tkv^{Q253D.UAS.cNb}

(Barrio et al., 2007)

Snoo^M67, Scer\GAL4^nub-AC-62 is a suppressor of wing phenotype of Mad^UAS.cNa, Scer\GAL4^nub-AC-62

(Barrio et al., 2007)

Snoo^M67, Scer\GAL4^nub-AC-62 is a suppressor of wing vein phenotype of Mad^UAS.cNa, Scer\GAL4^nub-AC-62

(Barrio et al., 2007)

Snoo^M67/Scer\GAL4^salm-459.2 is a suppressor of wing phenotype of Scer\GAL4^salm-459.2, babo^Q302D.UAS

(Barrio et al., 2007)

Snoo^M67/Scer\GAL4^salm-459.2 is a suppressor of wing vein phenotype of Scer\GAL4^salm-459.2, babo^Q302D.UAS

(Barrio et al., 2007)

Snoo^M67/Scer\GAL4^nub-AC-62 is a suppressor of wing phenotype of Scer\GAL4^nub-AC-62, babo^Q302D.UAS

(Barrio et al., 2007)

Snoo^M67/Scer\GAL4^nub-AC-62 is a suppressor of wing vein phenotype of Scer\GAL4^nub-AC-62, babo^Q302D.UAS

(Barrio et al., 2007)

Snoo^M67/Snoo^2c3 is a suppressor | partially of wing phenotype of Mad^UAS.cNa, Scer\GAL4^nub-AC-62

(Barrio et al., 2007)

Snoo^M67/Snoo^2c3 is a suppressor | partially of wing vein phenotype of Mad^UAS.cNa, Scer\GAL4^nub-AC-62

(Barrio et al., 2007)

Snoo^M67/Scer\GAL4^salm-459.2 is a suppressor of wing phenotype of Scer\GAL4^salm-459.2, tkv^{Q253D.UAS.cNb}

(Barrio et al., 2007)

NOT Suppressor of

Statement

Reference

Snoo^M67, Scer\GAL4^nub-AC-62 is a non-suppressor of wing phenotype of Med^UAS.cSa, Scer\GAL4^nub-AC-62

(Barrio et al., 2007)

Snoo^M67, Scer\GAL4^nub-AC-62 is a non-suppressor of wing vein phenotype of Med^UAS.cSa, Scer\GAL4^nub-AC-62

(Barrio et al., 2007)

Other

Statement

Reference

Scer\GAL4^nub-AC-62, Smox^UAS.cZa, Snoo^M67 has wing phenotype

(Barrio et al., 2007)

Scer\GAL4^nub-AC-62, Smox^UAS.cZa, Snoo^M67 has wing vein phenotype

(Barrio et al., 2007)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of Snoo^M67 rescues the wing phenotypes caused by Scer\GAL4^salm-459.2- or Scer\GAL4^nub-AC-62-mediated expression of tkv^{Q253D.Scer\UAS.cNb} or babo^{Q302D.Scer\UAS}.

Co-expression of Mad^Scer\UAS.cNa or Med^Scer\UAS.cSa suppresses the wing phenotypes caused by Scer\GAL4^salm-459.2-mediated expression of Snoo^M67, giving rise to wings of almost normal size and pattern.

Co-expression of Mad^Scer\UAS.cNa and Snoo^M67 using Scer\GAL4^nub-AC-62 results in wings with a normal pattern of veins.

Co-expression of Snoo^M67 does not suppress the Med^Scer\UAS.cSa, Scer\GAL4^nub-AC-62 wing phenotype. However, the vein phenotype seen in Snoo^M67, Scer\GAL4^nub-AC-62 wings is suppressed by co-expression of Med^Scer\UAS.cSa.

Co-expression of Snoo^M67 and Smox^Scer\UAS.cZa using Scer\GAL4^nub-AC-62 generates very small wings without veins.

(Barrio et al., 2007)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Snoo^M67 is rescued by Scer\GAL4^salm-459.2/Snoo^RNAi.UAS

(Barrio et al., 2007)

Comments

Co-expression of Snoo^{dsRNA.Scer\UAS} suppresses the reduced size and venation phenotypes seen in Snoo^M67, Scer\GAL4^salm-459.2 wings.

(Barrio et al., 2007)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Snoo^M67

Name Synonyms

Secondary FlyBase IDs

References (1)

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