FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\esclinc.esc.Tag:FLAG
Open Close
General Information
Symbol
Dmel\esclinc.esc.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0244358
Feature type
allele
Associated gene
Dmel\escl
Associated Insertion(s)
Carried in Construct
P{esc-Flag-escl.inc}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Ohno et al., 2008)
Progenitor genotype
Carried in construct
P{esc-Flag-escl.inc}
Cytology
Description

esc promoter sequences (nucleotides 2L:11829236-11830492 of the release 3 genome sequence) drive expression of cDNA sequences encoding the escl open reading frame (incompletely spliced variant, contains intron 2 sequences) and 3'UTR. The escl open reading frame is tagged at the N-terminal end with Tag:FLAG.

(Ohno et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
esc
Encoded product / tool
escl
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Other
      Statement
      Reference

      esc6, esclinc.esc.Tag:FLAG has sex comb | ectopic phenotype

      (Ohno et al., 2008)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The presence of esclinc.esc.T:Zzzz\FLAG permits the recovery of adult progeny in a homozygous esc6 stock. The rescued homozygous females are fertile, while the rescued males have extra sex combs on their legs.

      (Ohno et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      esclinc.esc.T:Zzzz\FLAG
      esclinc.esc.Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (1)