FlyBase Allele Report: Dmel\ewg[UAS.cHa]

General Information

Symbol

Dmel\ewg^UAS.cHa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Haussmann

FlyBase ID

FBal0244700

Feature type

allele

Associated gene

Dmel\ewg

Associated Insertion(s)

Carried in Construct

P{UAS-ewg.H}

Key Links

Transgenic product class

wild_type

(Haussmann et al., 2008)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Haussmann et al., 2008)

Mutagen

in vitro construct

(Haussmann et al., 2008)

Progenitor genotype

Carried in construct

P{UAS-ewg.H}

Cytology

Description

UAS regulatory sequences drive expression of the ewg NS isoform (including the ewg 3'UTR).

(Haussmann et al., 2008)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

ewg

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | larval stage | RU486 conditional, with Scer\GAL4^{elav.Switch.PO}

(Haussmann et al., 2008)

lethal - all die before end of pupal stage | RU486 conditional, with Scer\GAL4^{elav.Switch.PO}

(Haussmann et al., 2008)

some die during pupal stage | RU486 conditional, with Scer\GAL4^{elav.Switch.PO}

(Haussmann et al., 2008)

Phenotype Manifest In

embryonic/larval neuromuscular junction | RU486 conditional, with Scer\GAL4^{elav.Switch.PO}

(Haussmann et al., 2008)

NMJ bouton | RU486 conditional, with Scer\GAL4^{elav.Switch.PO}

(Haussmann et al., 2008)

Detailed Description

Statement

Reference

Larvae expressing ewg^Scer\UAS.cHa under the control of Scer\GAL4^{elav.Switch.PO} in the presence of RU486 show a reduction in the number of type 1b boutons at the larval neuromuscular junction compared to wild type.

(Haussmann et al., 2008)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

77879

y¹ w^*; P{UAS-ewg.H}3

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

ewg^Scer\UAS.cHa

ewg^UAS.cHa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Haussmann

Secondary FlyBase IDs

References (1)

Report Sections

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