FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\RanBPMs135
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General Information
Symbol
Dmel\RanBPMs135
Species
D. melanogaster
Name
FlyBase ID
FBal0244765
Feature type
allele
Associated gene
Dmel\RanBPM
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Scantlebury et al., 2010)
Progenitor genotype
P{lacW}RanBPMk05201
(Scantlebury et al., 2010)
Cytology
Description

Imprecise excision of the progenitor insertion, resulting in a deletion that eliminates a maximum of 4.1kb from the N-terminus to the middle of RanBPM (nucleotides 64747 to 68882 in AE003829).

(Scantlebury et al., 2010)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2R:10,428,362..10,432,497 [+]
Comment:

Deletion resulting from the imprecise excision of P{lacW}RanBPMk05201. Deletion extends from 64747 to 68882 of GB:AE003829.

(Scantlebury et al., 2010)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      RanBPMk05201/RanBPMs135 third instar larvae show a significantly lower response index (response index = (path length in dark - path length in light)/total path length during the assay) in an on/off light avoidance assay than control larvae.

      Homozygous larvae are smaller than control larvae of the same age from the early third instar stage onwards.

      A smaller fraction of homozygous early foraging third instar larvae that have been placed on a drop of yeast paste containing food dye after a 2 hour starvation period show food dye in the gut after 30 minutes on the yeast paste.

      (Scantlebury et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      RanBPMs135
      (Scantlebury et al., 2010)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)