FB2026_02 , released June 18, 2026
Allele: Dmel\kibra3
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General Information
Symbol
Dmel\kibra3
Species
D. melanogaster
Name
FlyBase ID
FBal0244821
Feature type
allele
Associated gene
Dmel\kibra
Associated Insertion(s)
P{EPgy2}EY03746
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Baumgartner et al., 2010)
Progenitor genotype
P{EPgy2}EY03746
(Baumgartner et al., 2010)
Associated Insertion(s)
P{EPgy2}EY03746
Cytology
Description

Point mutation in the kibra start codon (ATG to ATA). The P{EPgy2}EY03746 insertion present in the progenitor is still present.

(Baumgartner et al., 2010)
Allele components
Component
Use(s)
Inserted element
P{EPgy2}
Regulatory region(s)
UASp
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:14,723,571..14,723,571 [-]
Nucleotide change:

G14723571A

Reported nucleotide change:

G?A

Amino acid change:

M1I | kibra-PA; M1I | kibra-PB

Reported amino acid change:

M1I

Comment:

Generated through reversion mutagenesis of the line carrying P{EPgy2}kibraEY03746.

(Baumgartner et al., 2010)
transposable_element_insertion_site
3R:14,724,231..14,724,231 [-]
(Baumgartner et al., 2010)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Phenotype Manifest In
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Pupae with mosaic heads that are largely doubly mutant for exe1/exe1 and kibra1/kibra3 (clones induced using the eyFLP method without cell lethal) do not eclose and normal head structures are displaced by overgrown tissue.

      Eyes doubly homozygous for Mer4 and kibra3 (generated using the eyFLP method) show stronger overgrowth than eyes singly homozygous for Mer4.

      (Baumgartner et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      kibra3 was selected as a mutation that reverts the kibraEY03746 phenotype.

      (Baumgartner et al., 2010)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Kibra3
      (Baumgartner et al., 2010, Baumgartner et al., 2010)
      kibra3
      (Gusareva et al., 2018)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)