FlyBase Allele Report: Dmel\Rab27[JF02165]

General Information

Symbol

Dmel\Rab27^JF02165

Species

D. melanogaster

Name

FlyBase ID

FBal0244855

Feature type

allele

Associated gene

Dmel\Rab27

Associated Insertion(s)

Carried in Construct

P{TRiP.JF02165}

Also Known As

UAS-Rab27-RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Perkins et al., 2009)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Perkins et al., 2009)

Mutagen

in vitro construct

(Perkins et al., 2009)

Progenitor genotype

Carried in construct

P{TRiP.JF02165}

Cytology

Description

UAS regulatory sequences drive expression of an inverted repeat.

(Perkins et al., 2009)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-JF02165

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

long lived, with Scer\GAL4^238Y

(Lien et al., 2020)

long lived, with Scer\GAL4^Rab27.ORF

(Lien et al., 2020)

long lived, with Scer\GAL4^VT014429

(Lien et al., 2020)

long lived, with Scer\GAL4^VT049246

(Lien et al., 2020)

long lived | RU486 conditional, with Scer\GAL4^{elav.Switch.PO}

(Lien et al., 2020)

short lived, with Scer\GAL4^GMR16A06

(Lien et al., 2020)

short lived, with Scer\GAL4^MT11

(Lien et al., 2020)

Phenotype Manifest In

extracellular exosome, with Scer\GAL4^dsx.KI

(Corrigan et al., 2014)

male accessory gland secondary cell, with Scer\GAL4^dsx.KI

(Corrigan et al., 2014)

Detailed Description

Statement

Reference

Expression of Rab27^JF02165 driven by Scer\GAL4^phm.PO does not lead to developmental delay/arrest at the larval stage.

(Yamanaka et al., 2015)

Expression of Rab27^JF02165 in secondary cells under the control of Scer\GAL4^dsx.KI significantly reduces exosome secretion into the accessory gland lumen compared to controls.

(Corrigan et al., 2014)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

31887

y¹ v¹; P{TRiP.JF02165}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Rab27^JF02165

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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