FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\Sec24CDunspecified
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General Information
Symbol
Dmel\Sec24CDunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0245184
Feature type
allele
Associated gene
Dmel\Sec24CD
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

    (FlyBase Curators, 2025-)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In

        embryonic/first instar larval cuticle

        (Tearle and Nusslein-Volhard, 1987)

        embryonic dorsal epidermis

        (Forster et al., 2010)

        filopodium & embryonic leading edge cell

        (Forster et al., 2010)

        rough endoplasmic reticulum & embryonic dorsal epidermis

        (Forster et al., 2010)
        Detailed Description
        Statement
        Reference

        Mutant leading edge cells form fewer filopodia than wild type during dorsal closure.

        Dorsal epidermal cells have an abnormal shape in stage 16 mutant embryos (being cobblestone-shaped with a convex surface, instead of the flat cuboidal cells seen in wild type). The cuticle layer is missing in these embryos. The rough endoplasmic reticulum is bloated in the mutant epidermal cell (it forms flat cisternae in wild-type embryos).

        (Forster et al., 2010)

        ghounspecified mutant embryos have undifferentiated cuticle with traces of mouthparts visible.

        (Tearle and Nusslein-Volhard, 1987)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        Sec24CDunspecified
        ghounspecified
        stenunspecified
        Name Synonyms
        Secondary FlyBase IDs
        • FBal0086584
        • FBal0241647
        References (4)