FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\bru1UASp.cSa
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General Information
Symbol
Dmel\bru1UASp.cSa
Species
D. melanogaster
Name
FlyBase ID
FBal0245236
Feature type
allele
Associated gene
Dmel\bru1
Associated Insertion(s)
Carried in Construct
P{UASp-bru1.S}
Also Known As
UAS-bru
Key Links
Transgenic product class
wild_type
(Snee et al., 2007)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Snee et al., 2007)
Mutagen
in vitro construct
(Snee et al., 2007)
Progenitor genotype
Carried in construct
P{UASp-bru1.S}
Cytology
Description

UASp regulatory sequences drive expression of the entire bru1 coding region and parts of the 5' and 3' UTRs.

(Snee et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
bru1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  tauopathy
      modeled by Hsap\MAPTV337M.UAS
      (Shulman et al., 2014)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Most embryos derived from females expressing aretScer\UAS.P\T.cSa under the control of Scer\GAL4nos.UTR.T:Hsim\VP16 lack most or all abdominal segments. Dorsoventral polarity is not substantially altered in these embryos.

      (Snee et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The bicaudal phenotype of embryos derived from females expressing oskScer\UAS.P\T.cSa under the control of Scer\GAL4mat.αTub67C.T:Hsim\VP16 is not altered by co-expression of aretScer\UAS.P\T.cSa.

      (Snee et al., 2007)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      aretScer\UAS.P\T.cSa
      bru1Scer\UAS.P\T.cSa
      bru1UASp.cSa
      Name Synonyms
      Secondary FlyBase IDs
        References (4)