FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\SosJF01216
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General Information
Symbol
Dmel\SosJF01216
Species
D. melanogaster
Name
FlyBase ID
FBal0245508
Feature type
allele
Associated gene
Dmel\Sos
Associated Insertion(s)
Carried in Construct
P{TRiP.JF01216}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Ni et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Ni et al., 2008)
Mutagen
in vitro construct
(Ni et al., 2008)
Progenitor genotype
Carried in construct
P{TRiP.JF01216}
Cytology
Description

UAS regulatory sequences drive expression of an inverted repeat.

(Ni et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-JF01216
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of SosJF01216 under the control of Scer\GAL4en-e16E results in defects in wing growth and vein formation. The phenotype is more severe in males than females.

      (Ni et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      SosJF01216/Scer\GAL4GMR.PFa is an enhancer of visible | adult stage phenotype of Scer\GAL4GMR.PFa, egrUAS.cMa

      (Ruan et al., 2016)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      SosJF01216/Scer\GAL4GMR.PFa is an enhancer of eye phenotype of Scer\GAL4GMR.PFa, egrUAS.cMa

      (Ruan et al., 2016)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The dot-like small eye phenotype characteristic for flies expressing egrScer\UAS.cMa under the control of Scer\GAL4GMR.PFa is exacerbated further by co-expression of SosJF01216 RNAi resulting in a 'no eye' phenotype with necrosis-like tissue present.

      (Ruan et al., 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      SosJF01216
      Name Synonyms
      Secondary FlyBase IDs
        References (2)