FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\cato536
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General Information
Symbol
Dmel\cato536
Species
D. melanogaster
Name
FlyBase ID
FBal0246023
Feature type
allele
Associated gene
Dmel\cato
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(zur Lage and Jarman, 2010)
Progenitor genotype
P{SUPor-P}KG07568
(zur Lage and Jarman, 2010)
Cytology
Description

Imprecise excision of the progenitor insertion has resulted in a 1313bp deletion that removes the cato upstream region without removing any of the cato transcription unit. This deletion affects expression of the cato gene.

(zur Lage and Jarman, 2010)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2R:16,278,626..16,279,938 [-]
Comment:

Inferred boundaries of a 1313bp deletion resulting from the imprecise excision of P{SUPor-P}KG07568, which removes the region upstream of the cato gene.

(zur Lage and Jarman, 2010)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous embryos show frequent duplications of chordotonal neurons. The v'ch1 neuron is duplicated in 84.5% of abdominal segments. Of these, very few (1.8%) seem to be associated with duplicated scolopale cells with the remainder having a single scolopale cell. In most cases a single cap cell can clearly be seen associated with the duplicated neuron.

      (zur Lage and Jarman, 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Only 5% of abdominal segments contain a possible lch5 neuron in cato536 ; ato1 double homozygous embryos.

      The frequency of loss of one chordotonal organ from the lch5 lateral cluster of five chordotonal organs which is seen in Df(1)ase-1 mutant embryos is increased (28% of segments) if the embryos are also carrying one copy of cato536.

      (zur Lage and Jarman, 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      cato536
      (zur Lage and Jarman, 2010)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)