FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Scox1rev25.2
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General Information
Symbol
Dmel\Scox1rev25.2
Species
D. melanogaster
Name
FlyBase ID
FBal0246268
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Associated Insertion(s)
Cytology
Description

Imprecise excision of P{EPgy2}ScoxEY05333, leaving 473 bp of the P{EPgy2} element at the insertion site.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Scox1rev25.2/ScoxSH1783 ovaries are smaller than wild type. Most of the ovariole strings contain egg chambers up to stage 9, and some (abnormally small) stage 10 egg chambers are found, but later stages are always degenerated. The migration of the border cells, and the columnar monolayer organization and integrity of the follicular epithelium in stage 10 egg chambers are not affected. The posterior movement of the epithelial sheet, which starts at stage 9 and ends at stage 10, is affected in Scox1rev25.2/ScoxSH1783 mutants - many follicle cells remain over the nurse cells. And, in contrast to wild type, yolk is completely absent or barely detectable in the oocyte at late stages of oogenesis.

Scox1rev25.2/ScoxSH1783 flies have reduced locomotor ability (running, climbing and flight) which becomes more pronounced with age.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Scox1rev25.2
scox1rev25.2
Name Synonyms
Secondary FlyBase IDs
    References (1)