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General Information
Symbol
Dmel\klhl10UAS.cKa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Kaplan
FlyBase ID
FBal0246328
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of klhl10.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of klhl10Scer\UAS.cKa under the control of Scer\GAL4GMR.PS results in reduced eye size.

Expression of klhl10Scer\UAS.cKa in the eye driven by Scer\GAL4GMR.PU results in highly reduced eye size with disorganised ommatidia.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Suppressed by
Statement
Reference
NOT suppressed by
Statement
Reference

Scer\GAL4GMR.PS, klhl10UAS.cKa has abnormal size phenotype, non-suppressible by Cul3mds1/Cul3[+]

Other
Phenotype Manifest In
Enhanced by
Suppressed by
NOT suppressed by
Statement
Reference

Scer\GAL4GMR.PS, klhl10UAS.cKa has eye phenotype, non-suppressible by Cul3mds1/Cul3[+]

Additional Comments
Genetic Interactions
Statement
Reference

Coexpression of skapScer\UAS.T or Cul3Scer\UAS.T enhances the reduced eye phenotype of flies expressing klhl10Scer\UAS.cKa under the control of Scer\GAL4GMR.PS.

Cul306430/+, but not Cul3mds1/+, partially suppresses the reduced eye phenotype of flies expressing klhl10Scer\UAS.cKa under the control of Scer\GAL4GMR.PS.

Coexpression of Cul3Scer\UAS.T, skapScer\UAS.T and klhl10Scer\UAS.cKa under the control of Scer\GAL4GMR.PS results in lethality, with flies being unable to eclose.

Co-expression of sotiScer\UAS.cKa completely suppresses the eye phenotype resulting from the expression of klhl10Scer\UAS.cKa driven by Scer\GAL4GMR.PU

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
klhl10Scer\UAS.cKa
klhl10UAS.cKa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Kaplan
Secondary FlyBase IDs
    References (2)