Under control conditions, rtp1 homozygous third instar larvae do not display significant changes in the number of sensory axons per nerve, as compared to controls.
Response termination to light stimulus of dark-adapted retin1 mutant retinas is slower that that in wild-type flies. In contrast to 3 day old mutants, retinas of 7 day old homozygous retin1 as well as Df(3R)ED5147/retin1 mutants display prolonged depolarization afterpotential (PDA) compared with wild-types. The reduced PDA does does not appear to be attributable to an age-dependent loss of the rhabdomeres, because 7-day old retin1 flies retain the full complement of rhabdomeres, although the size of rhabdomeres declines slightly. Maintaining the flies in the dark does not fully suppress this phenotype, although there is a minor improvement.