FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\rtp1
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General Information
Symbol
Dmel\rtp1
Species
D. melanogaster
Name
FlyBase ID
FBal0246715
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Progenitor genotype
Associated Insertion(s)
Cytology
Description

Deletion that removes the translation initiation codon and the following two methionine codons of rtp. A heat shock inducible w marker is inserted in place of the deleted sequence.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Under control conditions, rtp1 homozygous third instar larvae do not display significant changes in the number of sensory axons per nerve, as compared to controls.

Response termination to light stimulus of dark-adapted retin1 mutant retinas is slower that that in wild-type flies. In contrast to 3 day old mutants, retinas of 7 day old homozygous retin1 as well as Df(3R)ED5147/retin1 mutants display prolonged depolarization afterpotential (PDA) compared with wild-types. The reduced PDA does does not appear to be attributable to an age-dependent loss of the rhabdomeres, because 7-day old retin1 flies retain the full complement of rhabdomeres, although the size of rhabdomeres declines slightly. Maintaining the flies in the dark does not fully suppress this phenotype, although there is a minor improvement.

External Data
Interactions
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Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (3)