FB2026_02 , released June 18, 2026
Allele: Dmel\α-Spec::β-Specα8.Ubi-p63E.Tag:MYC
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General Information
Symbol
Dmel\α-Spec::β-Specα8.Ubi-p63E.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0246998
Feature type
allele
Associated gene
α-Spec::β-Spec
Associated Insertion(s)
Carried in Construct
P{Ubi-p63E-α-Spec::β-Spec.α8}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Mazock et al., 2010)
Progenitor genotype
Carried in construct
P{Ubi-p63E-α-Spec::β-Spec.α8}
Cytology
Description

Ubi-p63E promoter sequences drive expression of β-Spec coding sequence where the ankyrin-binding repeat 14 is replaced by the ankyrin-binding repeat 8 from α-Spec. The protein is tagged with a Tag:MYC epitope.

(Mazock et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
Ubi-p63E
Encoded product / tool
α-Spec::β-Spec
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Statement
      Reference

      α-Spec::β-Specα8.Ubi-p63E.Tag:MYC is a non-suppressor of lethal phenotype of β-Specem6

      (Mazock et al., 2010)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of α-Spec::β-Specα8.Ubi-p63E.T:Hsap\MYC fails to suppress lethality found in β-Specem6 mutants, due to its lack of biological activity.

      (Mazock et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      α-Spec::β-Specα8.Ubi-p63E.T:Hsap\MYC
      α-Spec::β-Specα8.Ubi-p63E.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (2)