FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\burC95A.UAS
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General Information
Symbol
Dmel\burC95A.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0247481
Feature type
allele
Associated gene
Dmel\bur
Associated Insertion(s)
Carried in Construct
P{UAS-bur.C95A}
Key Links
Transgenic product class
missense_variant
(van der Knaap et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(van der Knaap et al., 2010)
Mutagen
in vitro construct
(van der Knaap et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-bur.C95A}
Cytology
Description

UASt regulatory sequences drive expression of a mutant form of bur which contains the amino acid replacement C95A (this results in a protein defective in glutamine hydrolysis).

(van der Knaap et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
bur
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of burC95A.Scer\UAS under the control of Scer\GAL4GMR.PF does not result in eye defects.

      (van der Knaap et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Simultaneous co-expression of burC95A.Scer\UAS and Usp7Scer\UAS.cKa under the control of Scer\GAL4GMR.PF results in defects in the eye similar to those caused by co-expression of burScer\UAS.cLa and Usp7Scer\UAS.cKa under the control of Scer\GAL4GMR.PF.

      (van der Knaap et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      burC95A.Scer\UAS
      burC95A.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)