sNPFMI01807/sNPFMI01807 and sNPFc00448/sNPFMI01807 mutant larvae have significantly reduced nociceptive movement responses following stimulation with a von Frey filament, compared to controls; sNPFMI01807/+ heterozygotes also have reduced mechanonociceptive behavior, and this is exacerbated by expression of sNPFdsRNA.UAS under the control of Scer\GAL4Ilp7.PY; sNPFMI01807 homozygotes have mildly increased latency of rolling in response to high temperature (local) stimulation, compared to controls.
sNPFMI01807/sNPF[+] is partially rescued by sNPF1.UAS/Scer\GAL4Ilp7.PY
sNPFMI01807/sNPF[+] is partially rescued by sNPF2.UAS/Scer\GAL4Ilp7.PY