FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\sNPFMI01807
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General Information
Symbol
Dmel\sNPFMI01807
Species
D. melanogaster
Name
FlyBase ID
FBal0247775
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    sNPFMI01807/sNPFMI01807 and sNPFc00448/sNPFMI01807 mutant larvae have significantly reduced nociceptive movement responses following stimulation with a von Frey filament, compared to controls; sNPFMI01807/+ heterozygotes also have reduced mechanonociceptive behavior, and this is exacerbated by expression of sNPFdsRNA.UAS under the control of Scer\GAL4Ilp7.PY; sNPFMI01807 homozygotes have mildly increased latency of rolling in response to high temperature (local) stimulation, compared to controls.

    External Data
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    Phenotypic Class
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Partially rescued by

    sNPFMI01807/sNPF[+] is partially rescued by sNPF1.UAS/Scer\GAL4Ilp7.PY

    sNPFMI01807/sNPF[+] is partially rescued by sNPF2.UAS/Scer\GAL4Ilp7.PY

    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (1)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    Name Synonyms
    Secondary FlyBase IDs
      References (3)