FlyBase Allele Report: Dmel\Arf6[ΔKG1]

General Information

Symbol

Dmel\Arf6^ΔKG1

Species

D. melanogaster

Name

FlyBase ID

FBal0247916

Feature type

allele

Associated gene

Dmel\Arf6

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Huang et al., 2009)

Progenitor genotype

P{SUPor-P}Arf6^KG02753

(Huang et al., 2009)

Cytology

Description

Imprecise excision of the progenitor insertion, resulting in a 1.4kb deletion that deletes all of the coding exons and the 3' UTR.

(Huang et al., 2009)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

nucleus | embryonic stage | maternal effect

(Lee et al., 2015)

Detailed Description

Statement

Reference

No apparent defects in cleavage furrows are observed in cleavage furrows in embryos derived from Arf51F^ΔKG1 mutant mothers, although patches of nuclear loss (nuclear fall-ot) are observed in some embryos.

(Lee et al., 2015)

The patterning defects in retinas expressing Arf51F^GD13822 under the control of Scer\GAL4^GMR.PF is enhanced by heterozygosity for Arf51F^ΔKG1.

(Johnson et al., 2011)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhancer of

Statement

Reference

Arf51F[+]/Arf6^ΔKG1 is an enhancer of ommatidium phenotype of Scer\GAL4^GMR.PF, cindr^{RNAi.PC.PD.UAS}

(Johnson et al., 2011)

Other

Statement

Reference

Arf6^ΔKG1, Arf6^GD13822, Dcr-2^UAS.cDa, Scer\GAL4^GMR.PF has retina phenotype

(Johnson et al., 2011)

Additional Comments

Genetic Interactions

Statement

Reference

The ommatidial patterning errors resulting from the expression of cindr^{dsRNA.PC.PD.Scer\UAS} via Scer\GAL4^GMR.PF are strongly enhanced in Arf51F^ΔKG1 heterozygotes.

(Johnson et al., 2011)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

Arf51F^ΔKG1

Arf6^ΔKG1

arf6^KO

(Lee et al., 2015)

dArf6^KO1

(Johnson et al., 2011)

dArf6^ΔKG#1

(Huang et al., 2009)

dArf6ΔKG#1

(Johnson et al., 2011)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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