FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Lsd-1RNAi.UAS.cBa
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General Information
Symbol
Dmel\Lsd-1RNAi.UAS.cBa
Species
D. melanogaster
Name
FlyBase ID
FBal0247951
Feature type
allele
Associated gene
Dmel\Lsd-1
Associated Insertion(s)
Carried in Construct
P{UAS-Lsd-1.RNAi.B}
Key Links
Transgenic product class
RNAi_reagent
(Beller et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Beller et al., 2010)
Mutagen
in vitro construct
(Beller et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-Lsd-1.RNAi.B}
Cytology
Description

UAS regulatory sequences drive expression of an inverted repeat of Lsd-1-RC sequences (nucleotides 437-858 and 440-856).

(Beller et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Lsd-1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Disease
      Evidence
      References
      model of  obesity
      CEA
      (Beller et al., 2010)
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies expressing Lsd-1dsRNA.Scer\UAS.cBa under the control of Scer\GAL4fat have double the fat content of control flies.

      Flies expressing Lsd-1dsRNA.Scer\UAS.cBa under the control of Scer\GAL4fat show increased resistance to starvation compared to control flies. Lipid droplet size in the fat body cells is moderately increased in these animals.

      (Beller et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Lsd-1RNAi.UAS.cBa
      Lsd-1dsRNA.Scer\UAS.cBa
      Lsd-1dsRNA.UAS.cBa
      Name Synonyms
      Secondary FlyBase IDs
        References (3)