FB2026_02 , released June 18, 2026
Allele: Dmel\MAPk-Ak25B
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General Information
Symbol
Dmel\MAPk-Ak25B
Species
D. melanogaster
Name
FlyBase ID
FBal0248528
Feature type
allele
Associated gene
Dmel\MAPk-Ak2
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Chen et al., 2010)
Progenitor genotype
P{EPgy2}EY11791
(Chen et al., 2010)
Cytology
Description

Imprecise excision of the progenitor insertion, resulting in a deletion of the promoter region and 5' portion of MAPk-Ak2.

(Chen et al., 2010)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous flies are more sensitive to oxidative stress (either 10mM paraquat or 2% hydrogen peroxide) compared to controls.

      (Tian et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      MAPk-Ak25B is rescued by MAPk-Ak2+tTa

      (Tian et al., 2014)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      MAPk-Ak25B
      dMK25B
      (Tian et al., 2014, Chen et al., 2010)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)