FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\grhRH.UAS.Tag:FLAG
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General Information
Symbol
Dmel\grhRH.UAS.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0248548
Feature type
allele
Associated gene
Dmel\grh
Associated Insertion(s)
Carried in Construct
P{UAS-grh.RH.FLAG}
Key Links
Transgenic product class
wild_type
(Harrison et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Harrison et al., 2010)
Mutagen
in vitro construct
(Harrison et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-grh.RH.FLAG}
Cytology
Description

UAS regulatory sequences drive expression of grh-RH which is tagged with Tag:FLAG.

(Harrison et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
grh
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Blastoderm embryos derived from females expressing grhRH.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4mat.αTub67C.T:Hsim\VP16 show defects in nuclear division. Anaphase bridges are seen between dividing nuclei, aberrant cell divisions which are perpendicular to the normal plane of division are seen and a lack of synchronicity in cell divisions is seen in approximately 50% of the embryos. There is an approximately 50% reduction in hatching of these animals compared to controls.

      (Harrison et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      grhRH.Scer\UAS.T:Zzzz\FLAG
      grhRH.UAS.Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (1)