FB2026_02 , released June 18, 2026
Allele: Dmel\LpR1Df
Open Close
General Information
Symbol
Dmel\LpR1Df
Species
D. melanogaster
Name
FlyBase ID
FBal0256688
Feature type
allele
Associated gene
Dmel\LpR1
Associated Insertion(s)
P{XP-U}LpR1Df
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Parra-Peralbo and Culi, 2011)
Mutagen
FLPase
(Parra-Peralbo and Culi, 2011)
Progenitor genotype
P{XP}d10508
(Parra-Peralbo and Culi, 2011)
P{XP}d03066
(Parra-Peralbo and Culi, 2011)
Associated Insertion(s)
P{XP-U}LpR1Df
Cytology
Description

Recombination between the two progenitor insertions has resulted in the deletion of the intervening sequence between them, producing a 19.7kb deletion that completely removes LpR1.

(Parra-Peralbo and Culi, 2011)
Allele components
Component
Use(s)
Inserted element
P{XP-U}
Regulatory region(s)
UAS
Also carries
FRT
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3R:25,740,717..25,760,445 [-]
Comment:

Deletion of LpR1 resulting from FLP-catalyzed recombination using the FRT-containing transposons P{XP}d10508 and P{XP}d03066.

(Parra-Peralbo and Culi, 2011)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      In the LpR1Df/+ and LpR1Df/LpR1Df larval brain, LNv neurons show decreased dendritic volume. The LpR1Df/LpR1Df optic lobe presents decreased lipid droplet density.

      The expression of LpR1UAS.H.GFP under the control of Scer\GAL4P2.4.Pdf in LpR1Df/LpR1Df, leads to LNv neurons in the larval brain to exuberant dendritic branches extended beyond the synaptic region.

      (Yin et al., 2021)

      Homozygous females lay eggs which hatch at rates similar to that of wild-type females.

      Homozygous stage 10 egg chambers have a normal neutral lipid content.

      Homozygous larval wing discs have normal levels of intracellular lipid droplets.

      (Parra-Peralbo and Culi, 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Df(3R)lpr1
      (Parra-Peralbo and Culi, 2011)
      LpR1DF
      (Rojo-Cortés et al., 2022)
      LpR1Df
      lpr1 Df
      (Kang et al., 2024)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)