FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\nmoUAS.cUa.GFP
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General Information
Symbol
Dmel\nmoUAS.cUa.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0256854
Feature type
allele
Associated gene
Dmel\nmo
Associated Insertion(s)
Carried in Construct
P{UAS-GFP-nmo.U}
Also Known As
UAS-GFP-Nmo
Key Links
Transgenic product class
wild_type
(FlyBase Curators, 2025-)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(FlyBase Curators, 2025-)
Mutagen
in vitro construct
(FlyBase Curators, 2025-)
Progenitor genotype
Carried in construct
P{UAS-GFP-nmo.U}
Cytology
Description

UAS regulatory sequences drive expression of nmo which is tagged with GFP.

(FlyBase Curators, 2025-)

FlyBase curator comment: this entry represents a transgenic construct where the particular construct used cannot be determined.

(FlyBase Curators, 2025-)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
nmo
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of nmoUAS.cUa.GFP under the control of Scer\GAL4tim.PU leads to longer circadian period of locomotor activity rhythms under constant darkness compared to control adults.

      (Yu et al., 2011)

      Expression of nmoScer\UAS.cUa.T:Avic\GFP under the control of Scer\GAL4BG380 does not result in any significant change in the number of boutons per muscle surface area at the neuromuscular junction in third instar larvae.

      Expression of nmoScer\UAS.cUa.T:Avic\GFP under the control of Scer\GAL4BG380 results in a significant reduction in the excitatory junctional current amplitude and in quantal content at the neuromuscular junction compared to wild type.

      (Merino et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4tim.PU/nmoUAS.cUa.GFP rescues nmoP1/Df(3L)Exel6279

      (Yu et al., 2011)

      Scer\GAL4unspecified/nmoUAS.cUa.GFP rescues nmoP1/Df(3L)Exel6279

      (Merino et al., 2009)
      Fails to rescue

      Scer\GAL4G14/nmoUAS.cUa.GFP fails to rescue nmoP1/Df(3L)Exel6279

      (Merino et al., 2009)
      Comments

      The reduced number of boutons per muscle surface area seen at the neuromuscular junction in nmoP1/Df(3L)Exel6279 is rescued by neuronal expression of nmoScer\UAS.cUa.T:Avic\GFP under the control of Scer\GAL4unspecified but not by expression of nmoScer\UAS.cUa.T:Avic\GFP under the control of Scer\GAL4G14.

      (Merino et al., 2009)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      nmoScer\UAS.cUa.T:Avic\GFP
      nmoUAS.cUa.GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (4)