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General Information
Symbol
Dmel\Gr5aUAS.cDa
Species
D. melanogaster
Name
Gustatory receptor 5a promoter construct of Dahanukar
FlyBase ID
FBal0256891
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-Gr5a
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of a full-length Gr5a cDNA.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of Gr5aScer\UAS.cDa in ab1C neurons, under the control of Scer\GAL4Gr21a.9.323 or Scer\GAL4Gr63a.PF, is sufficient to confer trehalose response in the ab1C neuron. Application of sucrose does not alter the firing rate of ab1C neuron expressing Gr5a. These neurons respond to application of glucose, m-glucoside, and melezitose.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

A Gr63a1 mutant background does not alter the response to trehalose, glucose, m-glucoside, or melezitose in flies expressing Gr5aScer\UAS.cDa in ab1C neurons, under the control of Scer\GAL4Gr21a.9.323 or Scer\GAL4Gr63a.PF.

Co-expression of Gr64fScer\UAS.cFa, Gr64eScer\UAS.cFa, Gr61aScer\UAS.cFa, Gr64bScer\UAS.cJa, Gr64cScer\UAS.cFa, or Gr64dScer\UAS.cFa does not result in any significant alteration in the response to trehalose, m-glucoside, melezitose and glucose, in flies expressing Gr5aScer\UAS.cDa in ab1C neurons, under the control of Scer\GAL4Gr21a.9.323 or Scer\GAL4Gr63a.PF.

Co-expression of Gr61aScer\UAS.cFa does not result in any significant alteration in the response to trehalose, m-glucoside, and melezitose, in flies expressing Gr5aScer\UAS.cDa in ab1C neurons, under the control of Scer\GAL4Gr21a.9.323 or Scer\GAL4Gr63a.PF.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Expression of Gr5aScer\UAS.cDa under the control of Scer\GAL4Gr5a.8.5 rescues the reduction in the electrophysiological response to the sugars trehalose, m-α-glucoside, glucose and melezitose that is seen in Gr5aΔEP5 flies.

Expression of Gr5aScer\UAS.cDa under the control of Scer\GAL4Gr5a.8.5 increases the mean proboscis extension response to all sugars whose responses are reduced in Gr5aΔEP5 flies.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Gr5aScer\UAS.cDa
Gr5aUAS.cDa
Name Synonyms
Gustatory receptor 5a promoter construct of Dahanukar
Secondary FlyBase IDs
    References (3)