FlyBase Allele Report: Dmel\Su(z)12[HMS00280]

General Information

Symbol

Dmel\Su(z)12^HMS00280

Species

D. melanogaster

Name

FlyBase ID

FBal0257179

Feature type

allele

Associated gene

Dmel\Su(z)12

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS00280}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMS00280}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMS00280

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell cycle | oogenesis, with Scer\GAL4^nanos.PG

(Taslim et al., 2023)

abnormal stress response | oogenesis, with Scer\GAL4^nanos.PG

(Taslim et al., 2023)

Phenotype Manifest In

female germline stem cell, with Scer\GAL4^nanos.PG

(Taslim et al., 2023)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Su(z)12^HMS00280/Scer\GAL4^R11F02.-FRT is an enhancer of decreased size | adult stage | somatic clone phenotype of Ecol\lexA^DBD.R85E08, Hsap\RELA^AD.Hsp70, rpr^{13xlexAop.cHa}

(Harris et al., 2020)

Su(z)12^HMS00280/Scer\GAL4^R11F02.-FRT is an enhancer of visible | adult stage | somatic clone phenotype of Ecol\lexA^DBD.R85E08, Hsap\RELA^AD.Hsp70, rpr^{13xlexAop.cHa}

(Harris et al., 2020)

NOT Enhancer of

Statement

Reference

Su(z)12^HMS00280, Scer\GAL4^wor.PA, Scer\GAL80^ase.PN is a non-enhancer of increased cell number | larval stage | dominant phenotype of ham²

(Rives-Quinto et al., 2020)

NOT Suppressor of

Statement

Reference

Su(z)12^HMS00280, Scer\GAL4^wor.PA, Scer\GAL80^ase.PN is a non-suppressor of increased cell number | dominant | larval stage phenotype of ham²

(Rives-Quinto et al., 2020)

Phenotype Manifest In

Enhancer of

Statement

Reference

Su(z)12^HMS00280/Scer\GAL4^R11F02.-FRT is an enhancer of wing | somatic clone phenotype of Ecol\lexA^DBD.R85E08, Hsap\RELA^AD.Hsp70, rpr^{13xlexAop.cHa}

(Harris et al., 2020)

NOT Enhancer of

Statement

Reference

Su(z)12^HMS00280, Scer\GAL4^wor.PA, Scer\GAL80^ase.PN is a non-enhancer of type II neuroblast | larval stage | increased number phenotype of ham²

(Rives-Quinto et al., 2020)

Su(z)12^HMS00280, Scer\GAL4^wor.PA, Scer\GAL80^ase.PN is a non-enhancer of larval brain | larval stage phenotype of ham²

(Rives-Quinto et al., 2020)

NOT Suppressor of

Statement

Reference

Su(z)12^HMS00280, Scer\GAL4^wor.PA, Scer\GAL80^ase.PN is a non-suppressor of type II neuroblast | increased number | larval stage phenotype of ham²

(Rives-Quinto et al., 2020)

Su(z)12^HMS00280, Scer\GAL4^wor.PA, Scer\GAL80^ase.PN is a non-suppressor of larval brain | larval stage phenotype of ham²

(Rives-Quinto et al., 2020)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

NIG-Fly

HMS00280

y¹ sc^* v¹ sev²¹; P{TRiP.HMS00280}attP2/TM3, Sb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Su(z)12^HMS00280

Su(z)12^RNAi

(Rives-Quinto et al., 2020)

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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