FB2026_03 , released September 17, 2026
Allele: Dmel\shnHMS01167
Open Close
General Information
Symbol
Dmel\shnHMS01167
Species
D. melanogaster
Name
FlyBase ID
FBal0257827
Feature type
allele
Associated gene
Dmel\shn
Associated Insertion(s)
Carried in Construct
P{TRiP.HMS01167}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Ni et al., 2010.12.1)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Ni et al., 2010.12.1)
Mutagen
in vitro construct
(Ni et al., 2010.12.1)
Progenitor genotype
Carried in construct
P{TRiP.HMS01167}
Cytology
Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-HMS01167
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of shnHMS01167 in the LNvs, under the control of Scer\GAL4P2.4.Pdf, renders 50% of flies arrhythmic, with a clear disorganisation of the activity profile, suggesting that shn is involved in locomotor circadian rhythms.

      (Beckwith et al., 2013)

      Expression of shnHMS01167 in C-I neurons under the control of Scer\GAL4221 results in ddaD neurons that have an increased number of dendritic branches compared to controls.

      Expression of shnHMS01167 in C-IV neurons under the control of shnHMS01167 results in a reduction in total dendritic length in ddaC and v'ada neurons. The total number of dendritic branches is also reduced in ddaC neurons.

      (Iyer et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4tim.PE/shnHMS01167 rescues shn756

      (Beckwith et al., 2013)
      Comments

      Co-expression of shnHMS01167 rescues the circadian phenotype seen upon overexpression of shn756.Scer\UAS under the control of Scer\GAL4tim.PE.

      (Beckwith et al., 2013)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      shnHMS01167
      Name Synonyms
      Secondary FlyBase IDs
        References (4)