FlyBase Allele Report: Dmel\Sema1a[HMS01307]

General Information

Symbol

Dmel\Sema1a^HMS01307

Species

D. melanogaster

Name

FlyBase ID

FBal0257900

Feature type

allele

Associated gene

Dmel\Sema1a

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS01307}

Also Known As

Sema1a RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMS01307}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMS01307

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

adult insulin secreting cell of pars intercerebralis, with Scer\GAL4^Ilp2.PR

(Clements et al., 2021)

adult insulin secreting cell of pars intercerebralis, with Scer\GAL4^repo.PL

(Clements et al., 2021)

adult Kenyon cell | P-stage, with Scer\GAL4^c305a

(Chu et al., 2024)

axon | P-stage, with Scer\GAL4^c305a

(Chu et al., 2024)

medulla intrinsic neuron Mi1 | P-stage, with Scer\GAL4^bsh.M.PT

(Bustillo et al., 2024)

medulla layer | P-stage, with Scer\GAL4^bsh.M.PT

(Bustillo et al., 2024)

medulla layer | P-stage, with Scer\GAL4^elav.PLu

(Bustillo et al., 2024)

medulla layer | P-stage, with Scer\GAL4^GMR9D03

(Bustillo et al., 2024)

medulla layer | P-stage, with Scer\GAL4^nSyb.PS

(Bustillo et al., 2024)

medulla layer M3 | P-stage, with Scer\GAL4^bsh.M.PT

(Bustillo et al., 2024)

medulla layer M3 | P-stage, with Scer\GAL4^GMR9D03

(Bustillo et al., 2024)

neurite | adult stage | ectopic, with Scer\GAL4^Ilp2.PR

(Clements et al., 2021)

neurite | adult stage | ectopic, with Scer\GAL4^repo.PL

(Clements et al., 2021)

neurite | P-stage, with Scer\GAL4^bsh.M.PT

(Bustillo et al., 2024)

neurite | P-stage, with Scer\GAL4^GMR9D03

(Bustillo et al., 2024)

transmedullary neuron Tm5 | P-stage, with Scer\GAL4^GMR9D03

(Bustillo et al., 2024)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Scer\GAL4^nSyb.PS, Sema1a^HMS01307 has abnormal neuroanatomy | P-stage phenotype, non-enhanceable by Sema1b^KO

(Bustillo et al., 2024)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Scer\GAL4^nSyb.PS, Sema1a^HMS01307 has medulla layer | P-stage phenotype, non-enhanceable by Sema1b^KO

(Bustillo et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

34320

y¹ sc^* v¹ sev²¹; P{TRiP.HMS01307}attP2

NIG-Fly

HMS01307

y¹ sc^* v¹ sev²¹; P{TRiP.HMS01307}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Sema-1a^HMS01307

Sema1a^HMS01307

Name Synonyms

Secondary FlyBase IDs

References (10)

Report Sections

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