FlyBase Allele Report: Dmel\wdb[12-1]

General Information

Symbol

Dmel\wdb^12-1

Species

D. melanogaster

Name

FlyBase ID

FBal0258007

Feature type

allele

Associated gene

Dmel\wdb

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Kotadia et al., 2008)

Progenitor genotype

Cytology

Description

Imprecise excision of an insertion at the 5' end of the gene, resulting in a 1.9kb deletion that removes both promoters.

(Kotadia et al., 2008)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die before end of pupal stage | recessive

(Kotadia et al., 2008)

some die during pupal stage | recessive

(Kotadia et al., 2008)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

wdb^12-1 has lethal | recessive phenotype, enhanceable by wrd^KG01108

(Kotadia et al., 2008)

Enhancer of

Statement

Reference

PP2A-B'[+], wdb[+], wdb^12-1, wrd^KG01108 is an enhancer of lethal | embryonic stage phenotype of SV40\ST^{UASp.Tag:FLAG}, Scer\GAL4^{VP16.nanos.UTR}

(Kotadia et al., 2008)

NOT Enhancer of

Statement

Reference

wdb[+]/wdb^12-1 is a non-enhancer of lethal | embryonic stage phenotype of SV40\ST^{UASp.Tag:FLAG}, Scer\GAL4^{VP16.nanos.UTR}

(Kotadia et al., 2008)

Other

Statement

Reference

wdb^12-1, wrd^KG01108 has lethal | third instar larval stage phenotype

(Kotadia et al., 2008)

Phenotype Manifest In

Enhancer of

Statement

Reference

wdb[+], wdb^12-1, wrd^KG01108 is an enhancer of centrosome | increased number phenotype of SV40\ST^{UASp.Tag:FLAG}, Scer\GAL4^{VP16.nanos.UTR}

(Kotadia et al., 2008)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

wdb^12-1

(Kotadia et al., 2008)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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