FB2026_02 , released June 18, 2026
Allele: Dmel\Nrx-1Δ174
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General Information
Symbol
Dmel\Nrx-1Δ174
Species
D. melanogaster
Name
FlyBase ID
FBal0258012
Feature type
allele
Associated gene
Dmel\Nrx-1
Associated Insertion(s)
Carried in Construct
Also Known As
dnrx174
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Zeng et al., 2007)
Progenitor genotype
Nrx-1d08766
(Zeng et al., 2007)
Cytology
Description

Mobilisation of P{XP}Nrx-1d08766 by Δ2-3 transposase results in a 1369bp deletion.

(Zeng et al., 2007)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3R:22,470,301..22,471,670 [+]
Comment:

Reported as a 1369 bp deletion resulting from the imprecise excsion of P{XP}Nrx-1d08766 extending from aaaacggattgccgagtaac to gagaaggagaaggcgccatc.

(Zeng et al., 2007)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  autism spectrum disorder
      modeled by Nrx-1Δ83
      (Guangming et al., 2023)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Nrx-1Δ174 and Nrx-1Δ174/Df(3R)Exel6191 mutants are viable and fertile, with no obvious developmental defects.

      (Zeng et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Nrx-1Δ174
      dnrx174
      (Zhao et al., 2024, Guangming et al., 2023, Xing et al., 2018)
      nrxΔ174
      (Tian et al., 2013)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)