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General Information
Symbol
Dmel\cicΔC2.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0258045
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
cicΔC2
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

A cic derivative lacking amino acids 1052-1072.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of cicΔC2.T:Ivir\HA1 has a strong maternal effect, resulting in embryonic lethality. The penetrance of this is high with a single copy of the transgene in approximately half of the transgenic lines. The remaining lines cause embryonic lethality only when two copies are present.

Embryos expressing strong cicΔC2.T:Ivir\HA1 insertions frequently lack the eight abdominal segment and the posterior spiracle. Stronger defects extending to the abdominal region are also observed in approximately 40% of the embryos.

Females expressing strong cicΔC2.T:Ivir\HA1 combinations produce eggs with partial or complete fusion of their dorsal respiratory appendages.

cicΔC2.T:Ivir\HA1 embryos are moderately ventralised.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

A single copy of weak cicΔC2.T:Ivir\HA1 insertions rescues the cic1 mutation to adulthood.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
cicΔC2.T:Ivir\HA1
cicΔC2.Tag:HA
Name Synonyms
Secondary FlyBase IDs
    References (3)