FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\stanΔIntra.UAS
Open Close
General Information
Symbol
Dmel\stanΔIntra.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0258316
Feature type
allele
Associated gene
Dmel\stan
Associated Insertion(s)
Carried in Construct
P{UAS-fmi.ΔIntra}
Also Known As
UAS-fmiΔIntra
Key Links
Transgenic product class
inframe_deletion
(Strutt and Strutt, 2008)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Strutt and Strutt, 2008)
Mutagen
in vitro construct
(Strutt and Strutt, 2008)
Progenitor genotype
Carried in construct
P{UAS-fmi.ΔIntra}
Cytology
Description

UAS regulatory sequences drive expression of a truncated form of stan which lacks the entire intracellular domain except for the first 30 amino acids after the last transmembrane domain.

(Strutt and Strutt, 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
stan
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      R7 photoreceptor axons extend normally to the M6 layer of the medulla in animals co-expressing gogoΔC.Scer\UAS.T:Hsap\MYC and stanΔIntra.Scer\UAS under the control of Scer\GAL4GMR.PU.

      Co-expression of gogoFL.Scer\UAS.T:Hsap\MYC and stanΔIntra.Scer\UAS under the control of Scer\GAL4GMR.PU results in a strong premature axon stopping phenotype in the R7 photoreceptor cells (41.0%).

      (Hakeda-Suzuki et al., 2011)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      stanΔIntra.UAS/Scer\GAL4GMR.PU rescues stanE59

      (Hakeda-Suzuki et al., 2011)
      Comments

      Expression of stanΔIntra.Scer\UAS under the control of Scer\GAL4GMR.PU rescues the axon targeting defects of homozygous single cell stanE59 R8 photoreceptor clones.

      (Hakeda-Suzuki et al., 2011)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      stanΔIntra.Scer\UAS
      stanΔIntra.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (3)