FB2026_02 , released June 18, 2026
Allele: Dmel\Fmr1WTRLN-ATG
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General Information
Symbol
Dmel\Fmr1WTRLN-ATG
Species
D. melanogaster
Name
FlyBase ID
FBal0258612
Feature type
allele
Associated gene
Dmel\Fmr1
Associated Insertion(s)
Carried in Construct
P{Fmr1.WTRLN-ATG}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Beerman and Jongens, 2011)
Progenitor genotype
Fmr1WTR
(Beerman and Jongens, 2011)
Carried in construct
P{Fmr1.WTRLN-ATG}
Cytology
Description

A CTG to CAG nucleotide substitution has been introduced at the alternative start codon and the normal start codon has been mutated from ATG to TTG. Only the long isoform is produced by this construct, at a higher level than is normally seen in wild-type flies.

(Beerman and Jongens, 2011)
Allele components
Component
Use(s)
Regulatory region(s)
Fmr1
Encoded product / tool
Fmr1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Fmr1WTRLN-ATG partially rescues Fmr13

      (Beerman and Jongens, 2011)
      Comments

      The increased number of boutons at the neuromuscular junction that is seen in Fmr13 larvae is rescued by Fmr1WTRLN-ATG. The high frequency of β-lobe crossover seen in the mushroom bodies of Fmr13 pharate adult brains is partially suppressed by Fmr1WTRLN-ATG.

      (Beerman and Jongens, 2011)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Fmr1WTRLN-ATG
      Name Synonyms
      Secondary FlyBase IDs
        References (1)