FlyBase Allele Report: Btau\RHO[ninaE.PA]

General Information

Symbol

Btau\RHO^ninaE.PA

Species

B. taurus

Name

neither inactivation nor afterpotential E promoter construct of Ahmad

FlyBase ID

FBal0258674

Feature type

allele

Associated gene

Btau\RHO

Associated Insertion(s)

Carried in Construct

P{ninaE-Rh1.A}

Also Known As

pRh1-Rho

Transgenic product class

cDNA

(Ahmad et al., 2006)

wild_type

(Ahmad et al., 2006)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Ahmad et al., 2006)

wild_type

(Ahmad et al., 2006)

Mutagen

in vitro construct

(Ahmad et al., 2006)

Progenitor genotype

Carried in construct

P{ninaE-Rh1.A}

Cytology

Description

A 3.0kb ninaE promoter fragment drives expression of a Btau\RHO cDNA. A 0.7kb fragment of the 3' untranslated region of ninaE is also present.

(Ahmad et al., 2006)

Allele components

Component

Use(s)

Regulatory region(s)

ninaE

Encoded product / tool

Btau\RHO

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressor of

Statement

Reference

Btau\RHO^ninaE.PA is a suppressor of rhabdomere phenotype of ninaE¹⁷

(Pinal and Pichaud, 2011, Ahmad et al., 2007)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Expression of Btau\RHO^ninaE.PA rescues the rhabdomere morphogenesis defects of ninaE¹⁷ flies.

(Pinal and Pichaud, 2011)

Btau\RHO^ninaE.PA is able to partially rescue the rhabdomere defects of ninaE¹⁷ flies. At 3 days of age, rhabdomere size is largely rescued, although they are smaller and slightly irregular in shape compared to wild type. At 7 days, more substantial defects in rhabdomere packing are seen in the rescued flies, and at 14 days the rhabdomere membranes are extensively unraveled. The unraveling phenotype is seen in 14 day old rescued flies raised both under light-dark conditions and raised under constant darkness.

(Ahmad et al., 2007)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Btau\RHO^ninaE.PA

Name Synonyms

neither inactivation nor afterpotential E promoter construct of Ahmad

Secondary FlyBase IDs

References (3)

Report Sections

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