FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\RootKK102209
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General Information
Symbol
Dmel\RootKK102209
Species
D. melanogaster
Name
FlyBase ID
FBal0259129
Feature type
allele
Associated gene
Dmel\Root
Associated Insertion(s)
Carried in Construct
P{KK102209}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Keleman et al., 2009.8.5)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Keleman et al., 2009.8.5)
Mutagen
in vitro construct
(Keleman et al., 2009.8.5)
Progenitor genotype
Carried in construct
P{KK102209}
Cytology
Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dsRNA-KK102209
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Adults expressing RootKK102209 under the control of Scer\GAL4elav-C155 show severe defects in climbing in a negative geotaxis assay.

      (Chen et al., 2015)

      The proximal centriole of the ciliary basal body is missing or mis-located in embryonic chordotonal neuron cilia of Scer\GAL4sca.PU RootletinKK102209 animals.

      Scer\GAL4sca.PU-mediated expression results in larvae showing reduced crawling path lengths, and adults that show impaired behaviour in a climbing assay that gets progressively worse with age. Knock-down larvae are also completely unable to responds to audio tones, while knock-down adults show a reduced response rate in a grooming assay.

      (Styczynska-Soczka and Jarman, 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      CG6129KK102209
      RootKK102209
      RootletinKK102209
      Name Synonyms
      Secondary FlyBase IDs
        References (3)