structural component of base of cilia - organizes rootlets at the base of primary cilia in sensory neurons - essential for sensory neuron functions, including negative geotaxis, taste, touch response, and hearing - rootlet assembly requires centrioles
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.49
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Root using the Feature Mapper tool.
Root is expressed in a dynamic pattern corresponding to developing sensory neuron lineages. Starting in stage 12 it is expressed in all precursor and progeny cells of type I sensory lineages of all sensory modalities (including olfactory, external sensory (mechanosensory and gustatory), and chordotonal (auditory and proprioceptive) neurons. Expression continues in these lineages but appears to become restricted to chordotonal neurons. Expression appears to occur exclusively and transiently in the lineages leading to cells that differentiate a cilium.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Root in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
The name "Rootletin" is based on sequence homology.