FlyBase Allele Report: Dmel\soul[KK111488]

General Information

Symbol

Dmel\soul^KK111488

Species

D. melanogaster

Name

FlyBase ID

FBal0259880

Feature type

allele

Associated gene

Dmel\soul

Associated Insertion(s)

Carried in Construct

P{KK111488}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK111488}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK111488

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

nucleus | decreased number | larval stage, with Scer\GAL4^phtm.PO

(Liu et al., 2024)

prothoracic gland | larval stage, with Scer\GAL4^phtm.PO

(Liu et al., 2024)

prothoracic gland | larval stage, with Scer\GAL4^spok.1.45

(Liu et al., 2024)

wing, with Scer\GAL4^Bx-MS1096

(Schertel et al., 2015)

Detailed Description

Statement

Reference

Expression of CG33557^KK111488 under the control of Scer\GAL4^Bx-MS1096 results in male flies with severe wing size and patterning defects.

Expression of CG33557^KK111488 under the control of Scer\GAL4^Bx-MS1096 results in female flies with severe wing size and patterning defects.

(Schertel et al., 2015)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^phtm.PO, soul^KK111488 has lethal - all die before end of larval stage phenotype, suppressible by Cpr49Ah^UAS.cDNA/pdm3^{UAS.ORF.GW.Tag:HA}, Scer\GAL4^phtm.PO

(Liu et al., 2024)

Scer\GAL4^phtm.PO, soul^KK111488 has decreased size | larval stage phenotype, suppressible by Cpr49Ah^UAS.cDNA/pdm3^{UAS.ORF.GW.Tag:HA}, Scer\GAL4^phtm.PO

(Liu et al., 2024)

NOT suppressed by

Statement

Reference

Scer\GAL4^phtm.PO, soul^KK111488 has decreased size | larval stage phenotype, non-suppressible by Cpr49Ah^UAS.cDNA, Scer\GAL4^phtm.PO

(Liu et al., 2024)

Scer\GAL4^phtm.PO, soul^KK111488 has decreased size | larval stage phenotype, non-suppressible by pdm3^{UAS.ORF.GW.Tag:HA}/Scer\GAL4^phtm.PO

(Liu et al., 2024)

Scer\GAL4^phtm.PO, soul^KK111488 has lethal - all die before end of larval stage phenotype, non-suppressible by Cpr49Ah^UAS.cDNA, Scer\GAL4^phtm.PO

(Liu et al., 2024)

Scer\GAL4^phtm.PO, soul^KK111488 has lethal - all die before end of larval stage phenotype, non-suppressible by pdm3^{UAS.ORF.GW.Tag:HA}/Scer\GAL4^phtm.PO

(Liu et al., 2024)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^phtm.PO, soul^KK111488 has prothoracic gland | larval stage phenotype, suppressible by Cpr49Ah^UAS.cDNA/pdm3^{UAS.ORF.GW.Tag:HA}, Scer\GAL4^phtm.PO

(Liu et al., 2024)

NOT suppressed by

Statement

Reference

Scer\GAL4^phtm.PO, soul^KK111488 has prothoracic gland | larval stage phenotype, non-suppressible by Cpr49Ah^UAS.cDNA, Scer\GAL4^phtm.PO

(Liu et al., 2024)

Scer\GAL4^phtm.PO, soul^KK111488 has prothoracic gland | larval stage phenotype, non-suppressible by pdm3^{UAS.ORF.GW.Tag:HA}/Scer\GAL4^phtm.PO

(Liu et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v109868

P{KK111488}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CG33557^KK111488

soul^KK111488

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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