FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\nsl1+t9.9
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General Information
Symbol
Dmel\nsl1+t9.9
Species
D. melanogaster
Name
FlyBase ID
FBal0260735
Feature type
allele
Associated gene
Dmel\nsl1
Associated Insertion(s)
Carried in Construct
P{wah9.9}
Key Links
Transgenic product class
genomic_DNA
(Yu et al., 2010)
wild_type
(Yu et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Yu et al., 2010)
wild_type
(Yu et al., 2010)
Mutagen
in vitro construct
(Yu et al., 2010)
Progenitor genotype
Carried in construct
P{wah9.9}
Cytology
Description

A 9.9 kb fragment including wah genomic DNA from BAC clone R48G17.

(Yu et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
nsl1
Encoded product / tool
nsl1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      A single copy of wah+t9.9 can rescue the age-dependent female infertility of wah1, nosBN/nosBN females. However, wah1, nosBN homozygotes expressing a single copy of wah+t9.9 exhibit age-dependent infertility, producing no eggs after the 8th day post-eclosion.

      (Yu et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      nsl1+t9.9 rescues nsl11/Df(3R)Exel8162

      (Yu et al., 2010)

      nsl1+t9.9 rescues nsl106536/Df(3R)Exel8162

      (Yu et al., 2010)

      nsl1+t9.9 rescues nsl1c04892/Df(3R)Exel8162

      (Yu et al., 2010)

      nsl1+t9.9 rescues nsl11

      (Yu et al., 2010)
      Comments

      A single copy of wah+t9.9 rescues the lethality of wah1 homozygotes and wah1, wah06536 and wahc04892 hemizygotes.

      wah+t9.9 rescues the reduced abdominal segments phenotype seen in embryos produced by nosΔBX, nosBN/nosBN females that are also heterozygous for wah1.

      (Yu et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      nsl1+t9.9
      wah+t9.9
      Name Synonyms
      Secondary FlyBase IDs
        References (1)