FlyBase Allele Report: Dmel\Pyk[GL00099]

General Information

Symbol

Dmel\Pyk^GL00099

Species

D. melanogaster

Name

FlyBase ID

FBal0262583

Feature type

allele

Associated gene

Dmel\Pyk

Associated Insertion(s)

Carried in Construct

P{TRiP.GL00099}

Also Known As

UAS-Pyk^RNAi, PyK RNAi, UAS-pyk-RNAi, PyK-RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2011.7.19)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2011.7.19)

Mutagen

in vitro construct

(Ni et al., 2011.7.19)

Progenitor genotype

Carried in construct

P{TRiP.GL00099}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2011.7.19)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-GL00099

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates Huntington's disease

modeled by Hsap\HTT^{N548.Q128.UAS}

(Martin et al., 2021)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

axon | larval stage, with Scer\GAL4^tey-5053A

(Waller et al., 2025)

axon | larval stage, with Scer\GAL4^unspecified

(Waller et al., 2025)

embryonic/larval neuromuscular junction | larval stage, with Scer\GAL4^Toll-6-D42

(Waller et al., 2025)

synapse | larval stage, with Scer\GAL4^Toll-6-D42

(Waller et al., 2025)

synaptic membrane | larval stage, with Scer\GAL4^Toll-6-D42

(Waller et al., 2025)

terminal tracheal cell | larval stage, with Scer\GAL4^btl.PS

(Hudson et al., 2023)

wing, with Scer\GAL4^C-765

(Spannl et al., 2020)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Pyk^GL00099, Scer\GAL4^unspecified has abnormal wound healing | larval stage phenotype, non-enhanceable by AMPKα^RNAi.UAS.cUa, Scer\GAL4^unspecified

(Waller et al., 2025)

Suppressed by

Statement

Reference

Pyk^GL00099, Scer\GAL4^Toll-6-D42 has abnormal neuroanatomy | larval stage phenotype, suppressible | partially by Sarm^KK100088, Scer\GAL4^Toll-6-D42

(Waller et al., 2025)

Pyk^GL00099, Scer\GAL4^Toll-6-D42 has abnormal neuroanatomy | larval stage phenotype, suppressible | partially by wnd^KK100521, Scer\GAL4^Toll-6-D42

(Waller et al., 2025)

Pyk^GL00099, Scer\GAL4^unspecified has abnormal wound healing | larval stage phenotype, suppressible | partially by wnd^KK100521, Scer\GAL4^unspecified

(Waller et al., 2025)

Pyk^GL00099, Scer\GAL4^unspecified has abnormal wound healing | larval stage phenotype, suppressible | partially by kay^Fbz.UAS, Scer\GAL4^unspecified

(Waller et al., 2025)

Pyk^GL00099, Scer\GAL4^unspecified has abnormal wound healing | larval stage phenotype, suppressible by Sarm^UAS.EGFP, Scer\GAL4^unspecified

(Waller et al., 2025)

NOT suppressed by

Statement

Reference

Pyk^GL00099, Scer\GAL4^unspecified has abnormal wound healing | larval stage phenotype, non-suppressible by AMPKα^RNAi.UAS.cUa, Scer\GAL4^unspecified

(Waller et al., 2025)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Pyk^GL00099, Scer\GAL4^unspecified has axon | larval stage phenotype, non-enhanceable by AMPKα^RNAi.UAS.cUa, Scer\GAL4^unspecified

(Waller et al., 2025)

Suppressed by

Statement

Reference

Pyk^GL00099, Scer\GAL4^Toll-6-D42 has synapse | larval stage phenotype, suppressible | partially by Sarm^KK100088, Scer\GAL4^Toll-6-D42

(Waller et al., 2025)

Pyk^GL00099, Scer\GAL4^Toll-6-D42 has synaptic membrane | larval stage phenotype, suppressible | partially by Sarm^KK100088, Scer\GAL4^Toll-6-D42

(Waller et al., 2025)

Pyk^GL00099, Scer\GAL4^Toll-6-D42 has synapse | larval stage phenotype, suppressible | partially by wnd^KK100521, Scer\GAL4^Toll-6-D42

(Waller et al., 2025)

Pyk^GL00099, Scer\GAL4^Toll-6-D42 has synaptic membrane | larval stage phenotype, suppressible | partially by wnd^KK100521, Scer\GAL4^Toll-6-D42

(Waller et al., 2025)

Pyk^GL00099, Scer\GAL4^unspecified has axon | larval stage phenotype, suppressible | partially by kay^Fbz.UAS, Scer\GAL4^unspecified

(Waller et al., 2025)

Pyk^GL00099, Scer\GAL4^unspecified has axon | larval stage phenotype, suppressible | partially by wnd^KK100521, Scer\GAL4^unspecified

(Waller et al., 2025)

Pyk^GL00099, Scer\GAL4^unspecified has axon | larval stage phenotype, suppressible by Sarm^UAS.EGFP, Scer\GAL4^unspecified

(Waller et al., 2025)

NOT suppressed by

Statement

Reference

Pyk^GL00099, Scer\GAL4^unspecified has axon | larval stage phenotype, non-suppressible by AMPKα^RNAi.UAS.cUa, Scer\GAL4^unspecified

(Waller et al., 2025)

NOT Enhancer of

Statement

Reference

Pyk^GL00099, Scer\GAL4^drm.7.1 is a non-enhancer of terminal tracheal cell | larval stage phenotype of Scer\GAL4^drm.7.1, trc^GL01127

(Hudson et al., 2023)

Suppressor of

Statement

Reference

Pyk^GL00099, Scer\GAL4^ppl.PP is a suppressor | partially of embryonic/larval fat body phenotype of Nadk1a^NIG.6145R, Scer\GAL4^ppl.PP

(Xu et al., 2021)

Pyk^GL00099, Scer\GAL4^ppl.PP is a suppressor | partially of mitochondrion | larval stage phenotype of Nadk1a^NIG.6145R, Scer\GAL4^ppl.PP

(Xu et al., 2021)

NOT Suppressor of

Statement

Reference

Pyk^GL00099, Scer\GAL4^drm.7.1 is a non-suppressor of terminal tracheal cell | larval stage phenotype of Scer\GAL4^drm.7.1, trc^GL01127

(Hudson et al., 2023)

Other

Statement

Reference

Pyk^GL00099, Scer\GAL4^drm.7.1, trc^GL01127 has embryonic/larval dorsal tracheal branch | larval stage phenotype

(Hudson et al., 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

35218

y¹ sc^* v¹ sev²¹; P{TRiP.GL00099}attP2

NIG-Fly

GL00099

y¹ sc^* v¹ sev²¹; P{TRiP.GL00099}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

PyK^GL00099

Pyk^GL00099

Name Synonyms

Secondary FlyBase IDs

References (11)

Report Sections

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