FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\VGATUAS.cFa
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General Information
Symbol
Dmel\VGATUAS.cFa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Fei
FlyBase ID
FBal0263507
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UAS regulatory sequences drive expression of a 1725bp VGAT coding sequence.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

VGATMB01219 mutant flies, expressing VGATScer\UAS.cFa under the control of Scer\GAL4VGAT and Scer\GAL80ts.αTub84B, to allow rescue past the embryonic lethality to the adult stage, exhibit normal ranges in wing beat frequency and amplitude. These flies do not exhibit differences in optomotor control capacity compared to controls.

VGATMB01219 mutant flies, expressing VGATScer\UAS.cFa under the control of Scer\GAL4VGAT and Scer\GAL80ts.αTub84B, show a reduced ability to fixate a stripe moving against a uniform white background and a diminished capacity for tracking a stripe moving against a counter-rotating wide-field background in which any displacement of the stripe is matched exactly by motion of the background in the opposite direction. General wide-filed optomotor function is intact in these mutants, while the behavioral deficit in these flies is specific for figure detection computations required to follow or fixate the direction of gaze on a small-field object, and more so for the control of response magnitude rather than timing.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
VGATScer\UAS.cFa
VGATUAS.cFa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Fei
Secondary FlyBase IDs
    References (1)