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General Information
Symbol
Dmel\Keap1dsRNA.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0263739
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-Keap1RNAi
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of an inverted repeat targeting Keap1 for RNAi mediated knockdown.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of Keap1dsRNA.Scer\UAS under the control of Scer\GAL4phm.PO results in delayed pupation compared to controls.

Pupae expressing Keap1dsRNA.Scer\UAS under the control of Scer\GAL4phm.PO are larger than control larvae.

Expression of Keap1dsRNA.Scer\UAS under the control of Scer\GAL4ple.PF has no effect on locomotor performance.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference

Flies co-expressing Hsap\SNCAScer\UAS.cTa and Keap1dsRNA.Scer\UAS under the control of Scer\GAL4ple.PF display locomotor activity similar to that of wild-type flies, indicating suppression of the age-dependent negative geotaxis response found in Hsap\SNCAScer\UAS.cTa-expressing flies.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Keap1dsRNA.Scer\UAS
Keap1dsRNA.UAS
Name Synonyms
Secondary FlyBase IDs
    References (7)