FB2026_02 , released June 18, 2026
Allele: Dmel\Fmr1ΔQN
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General Information
Symbol
Dmel\Fmr1ΔQN
Species
D. melanogaster
Name
FlyBase ID
FBal0263864
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

270bp deletion removing most of the codons specifying Q or N from the 3' exon.

Allele components
Component
Use(s)
Regulatory region(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially rescues
Comments

Fmr1ΔQN partially rescues the maternal effect embryonic lethality of Fmr13.

Fmr1ΔQN rescues the midline crossing phenotype of mushroom body β-lobe axons that is seen in Fmr13 adults.

Fmr1ΔQN does not rescue the increased number of boutons at the neuromuscular junction that is seen in homozygous Fmr13 larvae.

Fmr1ΔQN partially rescues the loss of rhythmic locomotion activity which is seen in Fmr13 flies under constant darkness conditions.

Fmr1ΔQN does not rescue the reduction in naive courtship activity seen in Fmr13 males. The defects in immediate recall after training are partially rescued, while the short-term memory defects seen after training are not rescued; the rescued males show some reduction in courtship index at 0-2 minutes after training but no reduction in courtship index at 60 minutes after training when placed with a receptive female.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Fmr1ΔQN
Name Synonyms
Secondary FlyBase IDs
    References (1)