FB2026_02 , released June 18, 2026
Allele: Dmel\Fmr1L
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General Information
Symbol
Dmel\Fmr1L
Species
D. melanogaster
Name
FlyBase ID
FBal0263866
Feature type
allele
Associated gene
Dmel\Fmr1
Associated Insertion(s)
Carried in Construct
P{Fmr1.L}
Key Links
Transgenic product class
cDNA
(Banerjee et al., 2010)
wild_type
(Banerjee et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Banerjee et al., 2010)
wild_type
(Banerjee et al., 2010)
Mutagen
in vitro construct
(Banerjee et al., 2010)
Progenitor genotype
Fmr1+t14
(Banerjee et al., 2010)
Carried in construct
P{Fmr1.L}
Cytology
Description

A NcoI/BspI genomic fragment from of the progenitor has been replaced with the corresponding fragment from the Fmr1 cDNA, removing sequences encoding the alternatively spliced intron. This results in a transgene that cannot produce the Fmr1-PB (Q/N-) isoform.

(Banerjee et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
Fmr1
Encoded product / tool
Fmr1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Fmr1L partially rescues Fmr13

      (Banerjee et al., 2010)
      Comments

      Fmr1L rescues the reduction in naive courtship activity seen in Fmr13 males, and the rescued males show normal short-term memory after training (showing a reduction in courtship index 60 minutes after training when placed with a receptive female). However, the rescued males show a deficit in long-term memory after training; they do not show a significant reduction in courtship index 4 days after training when placed with a receptive female.

      (Banerjee et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Fmr1L
      dfmr1L
      (Banerjee et al., 2010)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)