FB2026_02 , released June 18, 2026
Allele: Dmel\blanksdsRBD1+2
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General Information
Symbol
Dmel\blanksdsRBD1+2
Species
D. melanogaster
Name
FlyBase ID
FBal0264001
Feature type
allele
Associated gene
Dmel\blanks
Associated Insertion(s)
Carried in Construct
P{blanks.dsRBD1+2}
Key Links
Transgenic product class
missense_variant
(Sanders and Smith, 2011)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Sanders and Smith, 2011)
Mutagen
in vitro construct
(Sanders and Smith, 2011)
Progenitor genotype
P{blanks6}
(Sanders and Smith, 2011)
Carried in construct
P{blanks.dsRBD1+2}
Cytology
Description

The 'AA' residues within both the first and second double-stranded RNA binding domain of the P{blanks6} transgene are changed to 'KK' to abolish dsRNA binding and function.

(Sanders and Smith, 2011)
Allele components
Component
Use(s)
Regulatory region(s)
blanks
Encoded product / tool
blanks
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      blanksdsRBD1+2 fails to rescue blanksKG00804

      (Sanders and Smith, 2011)
      Comments

      The sterility and spermatid defects of homozygous blanksKG00804 males is not rescued by a blanksdsRBD1+2 transgene.

      (Sanders and Smith, 2011)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      blanksdsRBD1+2
      Name Synonyms
      Secondary FlyBase IDs
        References (1)