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General Information
Symbol
Dmel\per8:8
Species
D. melanogaster
Name
FlyBase ID
FBal0264019
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
P{dmper/8:8}
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

The per CRS (circadian regulatory sequence) and a basal Hsp70 promoter are fused upstream of sequences encoding the per coding region (a hybrid of cDNA and genomic sequences). The genomic portion includes the 3' UTR, including the 3' terminal intron. XhoI and KpnI sites have been introduced flanking this 3' terminal intron.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Transgenic per8:8 flies in a per01 mutant genetic background exhibit sleep patterns very similar to those previously described for wild-type strains, including the temperature and gender differences on daytime sleep.

per01 flies rescued with either perDyak\per.3' or perM2M1 generally show earlier onsets of evening activity and shorter, less robust, midday siestas compared to per01 flies rescued with per8:8.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Transgenic per8:8 flies in a per01 mutant genetic background exhibit sleep patterns very similar to those previously described for wild-type strains, including the temperature and gender differences on daytime sleep.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
per8:8
Name Synonyms
Secondary FlyBase IDs
    References (3)