FB2026_02 , released June 18, 2026
Allele: Dmel\UtxUAS.JmjC
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General Information
Symbol
Dmel\UtxUAS.JmjC
Species
D. melanogaster
Name
FlyBase ID
FBal0264576
Feature type
allele
Associated gene
Dmel\Utx
Associated Insertion(s)
Carried in Construct
PBac{UAS-Utx.JmjC}
Key Links
Transgenic product class
missense_variant
(Herz et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Herz et al., 2010)
Mutagen
in vitro construct
(Herz et al., 2010)
Progenitor genotype
Carried in construct
PBac{UAS-Utx.JmjC}
Cytology
Description

UASt drive expression of a Utx cDNA in which His883 is changed to Ala (CAC -> GCC) and Glu885 is changed to Ala (GAG -> GCG) within the JmjC domain. The encoded protein therefore lacks two residues critical for its catalytic function.

(Herz et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Utx
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      UtxUAS.JmjC/Scer\GAL4Sgs3.PD fails to rescue Utx1

      (Denton et al., 2013)

      UtxUAS.JmjC/Scer\GAL4Tub.PU fails to rescue Utx1

      (Herz et al., 2010)
      Comments

      Scer\GAL4Sgs3.PD-mediated expression of UtxScer\UAS.JmjC fails to rescue the delayed salivary gland degradation of the Utx1 mutant.

      (Denton et al., 2013)

      Expression of UtxScer\UAS.JmjC fails to revert the over-representation phenotype seen in mosaic Utx1 eye-antennal discs.

      (Herz et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      UtxScer\UAS.JmjC
      UtxUAS.JmjC
      Name Synonyms
      Secondary FlyBase IDs
        References (2)